Newsletter of the Meyer Cancer Center               February 2016
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Warming up to winter

In what I hope will be an auspicious start to the year ahead, the inaugural meetings of our re-aligned research programs were a success, with great attendance and engagement from cancer center members across disciplines. For those who were not able to attend, or who would like a reminder of some of the points I addressed, the slides from my overview remarks are available on the members resource page of our website. A schedule of upcoming meetings can also be found on individual research program pages. And don't forget to submit membership applications, as we update our list based on NCI criteria. 

Please join me in congratulating cancer center member and dean Laurie Glimcher on her appointment as president and chief executive officer of the Dana-Farber Cancer Institute. A respected colleague and friend for many years, her departure will be a great loss to the Cornell community, but we wish her well as she returns to Boston. I remain committed to carrying on the vision we have shared: to create an integrated, innovative epicenter of cancer research, care and education. I look forward to working with Laurie's successor to accomplish this, and I'm confident that with your help, we will continue to transform science-driven cancer care.

I'm looking forward to another exciting conference season in which we can engage our peers, and an expanded community outreach calendar in which to engage the public. Please let us know about your research, clinical and community activities, so that we can celebrate our collective accomplishments.



Long a pillar of cancer care, Silvia Formenti and Sandra Demaria are using radiation in a new way - to trigger a set of immune responses that converts tumors into personalized vaccines. Learn more about their work & other novel therapies at a new immunotherapy subsite, launched in conjuction with NewYork-Presbyterian's new #cancerunmasked campaign. 

Meet Monica

Supporting the team is crucial to making science happen. Meet Cantley Lab manager Monica Rosen.
Read more>>

Innovate, illuminate

A "cancer spray" and radiopharmaceuticals are among some of the innovations coming out of the 15th floor.
Read more>>

Preclinical pharmacy

Compounds are crucial to the creation of novel therapies. A new resource in the Cerchetti Lab is here to help.
Read more>>

In the headlines

Biologists urged to hug a preprint
Nature ~ February 18, 2016
Harold Varmus, M.D., discusses the idea of biomedical researchers releasing their work online before peer review and journal publication.

Among keys to curing cancer, academic medical centers loom large
The Hill ~ February 15, 2016
Dean Laurie Glimcher pens a guest piece about the role academic medical centers will have in realizing Vice President Joe Biden's "moonshot to cure cancer" campaign.

Gene sequencing effort helps pinpoint cancer treatments
NY1 ~ January 18, 2016
A two-part TV feature on how precision medicine is helping cancer patients at Weill Cornell/NYP.

See more>>

Funding opportunities

Damon Runyan Fellowship Award – Various; up to $60,000
The Pancreatic Cancer Detection Consortium (U01) – Pancreas
Cancer Research Education Grants Program - Research Experiences (R25) – Various; up to $300,000

See more>>


Recent Publications

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers
Mullarky E, Lucki NC, Beheshti Zavareh R, Anglin JL, Gomes AP, Nicolay BN, Wong JC, Christen S, Takahashi H, Singh PK, Blenis J, Warren JD, Fendt SM, Asara JM, DeNicola GM, Lyssiotis CA, Lairson LL, Cantley LC.
Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1778-83. doi: 10.1073/pnas.1521548113. Epub 2016 Feb 1.

Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas
Culjkovic-Kraljacic B, Fernando TM, Marullo R, Calvo-Vidal N, Verma A, Yang S, Tabbò F, Gaudiano M, Zahreddine H, Goldstein RL, Patel J, Taldone T, Chiosis G, Ladetto M, Ghione P, Machiorlatti R, Elemento O, Inghirami G, Melnick A, Borden KL, Cerchietti L.
Blood. 2016 Feb 18;127(7):858-68. doi: 10.1182/blood-2015-05-645069.

Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
Beltran H, Prandi D, Mosquera JM, Benelli M, Puca L, Cyrta J, Marotz C, Giannopoulou E, Chakravarthi BV, Varambally S, Tomlins SA, Nanus DM, Tagawa ST, Van Allen EM, Elemento O, Sboner A, Garraway LA, Rubin MA, Demichelis F.
Nat Med. 2016 Feb 8. doi: 10.1038/nm.4045.

The role of interventional oncology in the palliative care of
cancer patients

Li D., Hussaini S., Kang J., Madoff D.
Expert Review of Quality of Life in Cancer Care. 2016 Feb 5. doi: 10.1080/23809000.2016.1142358

Upcoming events

March 2, 2016

Higher-order chromatin architecture in cell fate decisions
Effie Apostolou, Ph.D.
Assistant Professor of Molecular Biology
Weill Cornell Medicine

New York Genome Center Five Points Lecture Series

March 16, 2016

Diabetes, obesity and cancer: Pharmacology & physiology at the interface
Michael Pollak, M.D.
Alexander Goldfarb Research Chair in Medical Oncology
Fellow, Canadian Academy of Health Sciences
Professor, McGill University

Meyer Cancer Center Seminar Series 2015/16

March 24, 2016

The Social Life of DNA
Alondra Nelson, Ph.D.
Dean of Social Science
Professor of Sociology
Columbia University

New York Academy of Medicine Events

See more>>

Dr. Lewis Cantley shares how practical teaching leads to medical breakthroughs
Meyer director Lewis Cantley shares how fundamental scientific discoveries translate to practical clinical innovations in this video from Cornell University.

Have some news or photos you'd like to share? Contact Stacey Shackford at
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