Editor: Sara Davies
February 24, 2017
HEART MONTH RECAP 

By yearly Presidential Proclamation, February has been marked as Heart Month since 1963. For the Pediatric and Congenital Heart Center of Alabama, it is a month to raise awareness of heart disease in children and celebrate the advances of our center. This is a month packed with activities.
  • There were over 100 attendees at the 3rd annual Journey of the Heart Cardiovascular Workshop held on Feb. 14.
  • The campaign to obtain a sufficient number of commitments for a Mending Kids’ Heart tag has almost reached the 1,000 necessary for the state to start printing the tag (sign up at www.childrensal.org/HeartTag; the first 1,000 sign ups are free for the first year).
  • The Benjamin Russell Building has been illuminated in red throughout the month of February.
  • Outreach through the website, Twitter, Facebook, print, and YouTube have emphasized patient stories and appearances by CV staff on local news outlets have promoted the many aspects of the heart center.
  • The center is in the midst of annual reports from each of its entities with half of them presenting last Wednesday and the other half presenting next Wednesday at 6:30 a.m. in the CV conference room. Some of the celebrated highlights have included:
    • 2016 surgical survival of 99.4% compared to the Society of Thoracic Surgeons registry 4-year rolling survival average of 96.5%. This is a testament to the multidisciplinary team of surgeons, intensivists, anesthesiologists, cardiologists, nurses, respiratory therapists, and so many others.
    • The CVICU CLABSI rate has decreased by 44% from 1.6/1000 line days to 0.9/1000 line days. Further efforts to decrease the rate to 0 are ongoing.
    • There was no catheter-associated UTI or ventilator-associated pneumonia in the CVICU.
    • Cardiac arrest rate has decreased by 31% from 7.1/1000 patient days to 4.9/1000 patient days. Our heart program is leading a 23-center collaborative to decrease cardiac arrest in the CICU.
    • Web-based home-monitoring program for high-risk patients initiated.
    • Cardiac ECMO program is part of the Children's of Alabama ELSO Platinum award-winning ECMO center with 83% neurologically intact survival for ECMO patients in 2016; ELSO average for cardiac patients is 46.7%.
Yung Lau, M.D. and Jeffrey Alten, M.D.
REGIONAL POISON CONTROL CENTER RELEASES ANNUAL REPORT 
 
The Regional Poison Control Center at Children’s of Alabama is thrilled to introduce our first electronic Annual Report.  We chose a few highlights that both healthcare professionals and the public would enjoy learning about our program. Please take a look to find 2016 data and information. 

View the report

Ann P. Slattery  DrPH, RN, RPh, CSPI, DABAT
Managing Director, Regional Poison Control Center
2nd ANNUAL PEDIATRIC SCIENCE DAY - MARCH 9
 
On March 9, we will celebrate the research efforts of our fellows and residents with our 2nd Annual UAB Pediatric Science Day! It will be a day to illustrate our research activities and support collaboration between young investigators. We are delighted to have received numerous abstract submissions, and we have put together an exciting day!
 
Topics will focus on research activities, quality improvement projects, and clinical case reports. The day will begin with coffee at 7:30 a.m., followed by a special Pediatric Science Day Morning Report at 8 a.m. All events will be held in the Bradley Lecture Hall. Our day will include sessions of oral presentations, a guest lecture by Dr. Michael Haller, Professor and Chief of Pediatric Endocrinology at the University of Florida, for Pediatric Grand Rounds, and will conclude with a poster session and light hors d’oeuvres in the afternoon.
 
We look forward to you joining us! 
Pediatric Science Day Program and Abstract
 
Please contact Michael Stalvey, M.D. or Ann Klasner, M.D. with questions.  
ALL CHIF AND PEDIATRIC FELLOW CORE CONFERENCES WILL BE HELD IN SURGERY COMMONS

Effective March 3, All Child Health Investigative Forum (CHIF) and Pediatric Fellow Core Conferences are relocating meetings to the Surgical Commons Conference Area. This newly-renovated space is located at the end of the hall on the 3rd floor of the Lowder Building. These conferences are from Noon to 1 p.m. and lunch is provided for the first 30 in attendance.

Child Health Investigative Forum (CHIF) | 1st and 3rd Fridays of the month | Surgical Commons
Questions? Contact Cassandra Hudson
*Exception: The April 7 CHIF meeting will be held in the Bradley. 

Pediatric Fellow Core Conferences | 2nd Friday of the month | Surgical Commons
Questions? Contact Ronda Chandler
DR. PRUITT ELECTED TO SSPR EXECUTIVE COUNCIL

Christopher Pruitt, M.D., 
Pediatric Emergency Medicine, has been elected to a second two-year term to the Southern Society for Pediatric Research (SSPR) Executive Council. Dr. Pruitt will serve on the council until February 2019. His responsibilities include mentorship of trainee research, judging for trainee research awards, and conference organization.
NOMINATE YOUR COLLEAGUES FOR 2017 DEAN'S EXCELLENCE AWARDS

Nominations are now open for the 2017 Dean’s Excellence Awards, an annual honor established to recognize the outstanding contributions made by faculty across the School of Medicine.

Two awards will be given each year—one to a junior faculty member (instructor or assistant professor) and the other to a senior faculty member (associate professor or full professor)—in the areas of service, teaching, research, diversity enhancement, and mentorship.  All full-time faculty members are eligible for nomination. View profiles of previous award winners. Any full-time faculty member may nominate a faculty colleague for any of these awards and self-nominations will be accepted.

Deadline: March 3 | More information.
JCMS AND GIRLS INC. LOOKING FOR PHYSICIANS WILLING TO HAVE SHADOWERS IN JUNE

On June 29-30, the Jefferson County Medical Society (JCMS) is partnering with Girls, Inc. to present a program on healthcare career opportunities to the girls who are participating in the Eureka! STEM (Science, Technology, Engineering, and Math) program.
Help them make this project a success! To allow a student to shadow you in the office or offer any suggestions, please contact Martha Wise at mwise@jcmsalabama.org or 205.933.8601.
Download the Flyer.
PEDIATRICS FACULTY EVALUATION DUE NEXT WEDNESDAY 

The 2016 Department of Pediatrics Faculty Evaluation process is well underway. All DOP faculty are expected to complete a self-evaluation by March 1. Evaluations may be accessed from any personal computer using the following URL: https://fe-prod.peds.uab.edu/FacultyEvaluation/Current. Use your Children’s login and password to access. If you attempt to log in from a clinic on a shared computer, you will likely be denied access. Contact Matt Duncan via the Peds Help Desk or Clare Mallette, if you need assistance.  
UAB-HUDSONALPHA CGM POSTDOC TRAINING PROGRAM ACCEPTING APPLICATIONS

UAB-HudsonAlpha Center for Genomic Medicine is now accepting applications for our UAB-HA Genomic Medicine Post-Doctoral Training program from trainees who are interested in pursuing a career in Genomic Medicine. The purpose of this training grant is to recruit postdoctoral trainees from various disciplines and provide mentorship and clinical research training in genomic medicine. 

Deadline: April 1 | More Information
DRY EYE & CONTACT LENS STUDY

The UAB School of Optometry Clinical Eye Research Facility (CERF) is conducting a study targeting subjects with dry eyes or contact lens wearers. 
They are looking for subjects over 18 who suffer from dry eye and contact lens wearers (primarily Oasys, Biofinity, Vita, and Ultra lenses). Click here for more information. 
IN THE NEWS 
UAB TO BRING PROTON THERAPY FOR ADVANCED CANCER TREATMENT TO BIRMINGHAM 

UAB will partner with Proton International to bring proton therapy, one of the most technically advanced forms of cancer-killing radiation, to Alabama. Proton therapy delivers a more precise dose of radiation to a tumor and can avoid damage to healthy surrounding tissue better than conventional X-ray radiation. 

“Proton therapy is particularly beneficial for children, as they are especially vulnerable to damage from radiation,” said Alyssa Reddy, M.D., professor of hematology/oncology in the UAB Department of Pediatrics. “Conventional radiation can help cure a child’s cancer, but it carries an increased risk of damage to surrounding tissue. In children, tissue damage, particularly in still-developing organs such as the brain, can leave the child susceptible to myriad health issues that may not emerge for years. Proton therapy offers the opportunity to successfully treat pediatric tumors and minimize the risk for side effects later in life. This will improve the health and quality of life of pediatric cancer survivors, most of whom we expect to live long and productive lives.”

Read this story at UAB News
SAVE THESE DATES
ATTEND THE OPIOID CRISIS IN ALABAMA: FROM SILOS TO SOLUTIONS 

Friday, March 10 | 9 a.m. - 3:30 p.m. | Montgomery, AL 

The Opioid Crisis in Alabama: From Silos to Solutions event will provide an overview of the opioid crisis in our state and nation and primer on addiction and evidence-based treatment, featuring speakers from across the country who will discuss solutions that have been successful in other states. The goal of the summit is to examine policy change aimed at reducing opioid-related overdose deaths in Alabama.
More information
RARE DISEASE DAY ADVOCACY EVENT 

March 1 | State Capitol | Montgomery, AL 

Join patients, families, caregivers, medical professionals, and industry representatives at this important event to discuss the challenges rare disease patients face and learn how you can make a difference in the lives of rare disease patients and their families in the state of Alabama.
Download the flyer.  | Register
PEDIATRIC GRAND ROUNDS - UP NEXT: 

Thursday, March 2 | Noon | Bradley Lecture Center

“Chest Wall Disorders in Children”
Gregory J. Redding, MD
Professor, Department of Pediatrics, University of Washington School of Medicine
Seattle Children’s Hospital, Seattle, WA

Click here to view the March Pediatrics Grand Rounds schedule
4TH FRIDAYS - TODAY!

Scott L. Phillips, Ph.D.
Director, UAB Center for Teaching and Learning (CTL)

"Active Learning Techniques"
Feb. 24 | Noon - 1 p.m. | Bradley Lecture Center 
Click here to download the flyer. 
RARE DISEASE EVENTS NEXT WEEK 

Thursday, March 2 | 5 - 7 p.m. | Bradley Lecture Center.
Art Exhibit Reception "Beyond the Diagnosis"


Children's of Alabama is hosting a reception for the traveling art exhibit, “Beyond the Diagnosis,” which artists have donated their time and talents to paint patients who have rare diseases. Children’s is pleased to join medical schools, research institutes and hospitals around the globe in hosting this exhibit to raise awareness of the need for more timely diagnoses and improved care for children with rare diseases.
Click here for the art exhibit invitation

Friday, March 3 | 8 a.m. - 3:30 p.m. | Bradley Lecture Center
4th Annual Rare Disease Genomics Symposium

To see the agenda, learning objectives, and speakers, click here
Register here for the symposium: www.ChildrensAl.org/genetics
FELLOWSHIP NEWS 
EMERGENCY MEDICINE FELLOW WINS FIRST PLACE AT SSPR

Kathleen Richard, M.D.,
Pediatric Emergency Medicine fellow, presented at the Southern Society for Pediatric Research (SSPR) annual meeting. Dr. Richard
was awarded first place for her podium presentation for the Pediatric Clinical Case Symposium.
FROM THE PEDIATRIC RESIDENCY OFFICE
QUARTERLY REMINDER ABOUT ANONYMOUS SUGGESTION BOX

Residents, Faculty, and Fellows are welcome to submit anonymous suggestions for the residency program directors. The Residency Program Suggestion Box is available year-round. Click here to access the survey: https://www.surveymonkey.com/r/59T7J69 

PEDIATRIC RESIDENT BOOK DRIVE FOR RNICU

The UAB Pediatric Residency Coat of Arms is hosting a book drive for the RNICU. We are collecting books (and/or funds to buy books) for young children ages 0-3 years through February 24. Please see flyer for details
FROM THE OFFICE OF FACULTY DEVELOPMENT (OFD) 
FREE WEBINARS IN THE ACW WINTER WEBINAR SERIES

Academic Branding: Improving Your Visibility, Network, and Career Opportunities
Academic Branding puts you in the driver's seat, allowing you to tell the story you want to tell about yourself, your scholarship, and your leadership.
March 2 | REGISTER HERE

Bringing Your Brand to Life Online
This webinar will introduce you to the most popular online platforms and tools to help you decide which resources to use to promote yourself and your academic work. 
March 30 | REGISTER HERE
FROM THE PEDIATRIC RESEARCH OFFICE (PRO) 
FUNDING
 
Community Health Innovation Awards (CHIA) Registration to Close Soon
These awards provide up to $25,000 for projects offering innovative solutions to Birmingham health concerns. Registration will close March 1 at 5 p.m. and all participants must be registered to attend the mandatory CHIA workshop on March 4. More information is available here.
 
Promoting Multiple R01 Investigators
This incentive is open to investigators who have one R01 and are seeking a second R01. It provides $50,000 for the initial year toward submission of an application and, based on score and critiques, an additional $50,000 in the second year to help with preliminary data and resubmission. Intent to submit is due March 6 at 5 p.m. and more information is available here.   
 
SEMINARS AND TRAINING
 
UAB Research Orientation Program
This program provides a basic overview of the clinical, regulatory and financial aspects of conducting a research study and offers 4 AMA PRA Category 1 credits. It will be held Monday, Feb. 27 from 8 a.m. - 12 p.m. in PCAMS (located at 1924 7th Ave So.).  Registration is required.

CCTS Monthly Forum: Innovating in Healthcare
This Forum will be held on March 1 from 4:45 - 6 p.m. in PCAMS (1924 7th Ave So) and will feature Dr. Erik Schwiebert, CEO and Chief Scientific Officer of DiscoveryBioMed. You can join in person for hors d’oeuvres and refreshments or online via GoToMeeting. More information is available here.
 
NHLBI Progenitor Cell Biology Consortium Cardiovascular Tissue Engineering Symposium
This event will be hosted by Dr. Zhang, Chair of UAB Biomedical Engineering, March 2-3 at UAB. Registration is free but required.

Alabama Drug Discovery Alliance (ADDA) Lecture Series
This CCTS-sponsored drug discovery lecture series runs on Mondays from 12 - 1 p.m. in PCAMS (located at 1924 7th Ave So) from March 7 to May 9. The first lecture, Intro to Drug Discovery and Its Funding, will be presented by Maaike Everts. Information on other presentations and the GoToMeeting link are available here.
 
ClinicalTrials.gov Final Rule Seminar
This PRO-sponsored seminar will be held in the Bradley Center from 2 - 3pm on Wednesday, March 15. Penny Jester will present new ClinicalTrials.gov requirements and how they impact your research.
 
Society for Redox Biology and Medicine (SfRBM) Regional Symposium: Translational Redox Biology
Held at the UAB Hill Center on March 16-17, this forum will discuss the rapidly evolving landscape in redox signaling paradigms and feature lectures from leaders in the field and especially from up-and-coming junior faculty, postdocs and students from UAB and regional institutions.  For more information, visit http://sfrbm.org/meetings/regional-symposium/
PRE - AWARD RESEARCH

eRA Latest News
 
GRANT AWARDS
Wynton Hoover (Ped - Pulmonary) TRI-STAR Initial and Chronic MRSA Infection in CF University of North Carolina at Chapel Hill.  $16,284. 04/01/2016 - 03/31/2017.

Wynton Hoover (Ped - Pulmonary) Pediatric Physical Therapist Award Cystic Fibrosis Foundation. $30,000. 11/01/2016 - 10/31/2017.
PUBLICATIONS
Medicine (Baltimore). 2016 Sep;95(39):e4909. doi: 10.1097/MD.0000000000004909. In vivo expansion and activation of γδ T cells as immunotherapy for refractory neuroblastoma: A phase 1 study. Pressey JG, Adams J, Harkins L, Kelly D, You Z, Lamb LS Jr.

J Inherit Metab Dis. 2017 Feb 15. doi: 10.1007/s10545-017-0015-9. Mild orotic aciduria in UMPS heterozygotes: a metabolic finding without clinical consequences. Wortmann SB, Chen MA, Colombo R, Pontoglio A, Alhaddad B, Botto LD, Yuzyuk T, Coughlin CR, Descartes M, Grűnewald S, Maranda B, Mills PB, Pitt J, Potente C, Rodenburg R, Kluijtmans LA, Sampath S, Pai EF, Wevers RA, Tiller GE; and additional individual contributors.
This study utilized the National Cancer Data Base to determine whether institutional surgical volume impacted surgical outcomes for Wilms tumor. Children operated on at high volume centers were more likely to undergo recommended lymph node sampling and had fewer days to initiation of chemotherapy than low volume centers. These differences did not, however, affect overall survival.

J Pediatr Surg. 2017 Jan;52(1):104-108. doi: 10.1016/j.jpedsurg.2016.10.029. The association between nephroblastoma-specific outcomes and high versus low volume treatment centers. Richards MK, Goldin AB, Savinkina A, Doski J, Goldfarb M, Nuchtern J, Langer M, Beierle EA, Vasudevan S, Gow KW, Raval MV.

This study utilized the National Cancer Data Base to determine whether institutional surgical volume impacted surgical outcomes for Wilms tumor. Children operated on at high volume centers were more likely to undergo recommended lymph node sampling and had fewer days to initiation of chemotherapy than low volume centers. These differences did not, however, affect overall survival.

J Neurosurg Pediatr. 2016 Sep;18(3):320-4. doi: 10.3171/2016.3.PEDS15648. Surgeon interrater reliability in the endoscopic assessment of cistern scarring and aqueduct patency. He L, Gannon S, Shannon CN, Rocque BG, Riva-Cambrin J, Naftel RP.

J Neurosurg Pediatr. 2016 Sep;18(3):287-95. doi: 10.3171/2016.3.PEDS15364. Radiographic markers of clinical outcomes after endoscopic third ventriculostomy with choroid plexus cauterization: cerebrospinal fluid turbulence and choroid plexus visualization.
Pindrik J, Rocque BG, Arynchyna AA, Johnston JM, Rozzelle CJ.


PLoS One. 2017 Feb 16;12(2):e0171473. doi: 10.1371/journal.pone.0171473. eCollection 2017. Autologous hematopoietic stem cell transplantation in lymphoma patients is associated with a decrease in the double strand break repair capacity of peripheral blood lymphocytes. Lacoste S, Bhatia S, Chen Y, Bhatia R, O'Connor TR.
Two messages emerge from this study. DNA repair capacity declines with age, and also decreases after hematopoietic cell transplantation, placing aging individuals after hematopoietic cell transplantation at increased risk for subsequent neoplasms.

J Neurosurg Pediatr. 2017 Feb;19(2):157-167. doi: 10.3171/2016.8. PEDS16229. Ventricular catheter entry site and not catheter tip location predicts shunt survival: a secondary analysis of 3 large pediatric hydrocephalus studies. Whitehead WE, Riva-Cambrin J, Kulkarni AV, Wellons JC 3rd, Rozzelle CJ, Tamber MS, Limbrick DD Jr, Browd SR, Naftel RP, Shannon CN, Simon TD, Holubkov R, Illner A, Cochrane DD, Drake JM, Luerssen TG, Oakes WJ, Kestle JR;  for the Hydrocephalus Clinical Research Network.

Vaccine. 2017 Feb 16.
pii: S0264-410X(17)30162-7. doi: 10.1016/j.vaccine.2017.01.082. Rotavirus immunization: Global coverage and local barriers for implementation. Lo Vecchio A, Liguoro I, Dias JA, Berkley JA, Boey C, Cohen MB, Cruchet S, Salazar-Lindo E, Podder S, Sandhu B, Sherman PM, Shimizu T, Guarino A.
We undertook an international survey of rotavirus vaccination policies. After 10 years since its introduction, the implementation of rotavirus immunization is still unacceptably low and should remain a major target for global public health. 
The deadline for submission of information for inclusion in the FYI Fridays newsletter is 10 a.m. on the preceding Thursday.
 
Click here to submit information to FYI Fridays.
FYI FRIDAYS ARCHIVE
Copyright © 2017 The UAB Department of Pediatrics, All rights reserved.


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