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Editor: Sara Davies 
OCTOBER 14, 2016
PEDIATRIC FACULTY AWARDS RECEPTION - MONDAY OCT. 17
 
The UAB Department of Pediatrics believes that recognizing the exceptional contributions of our faculty and colleagues is a vital aspect of our culture. The Department will be honoring individuals with the following awards on Monday, Oct. 17, at 3:30 p.m. in the Bradley Lecture Center. Please plan to join us as we recognize faculty at the first Pediatric Faculty Achievement Awards Reception.

Awards will be given in the following categories:
  • Lifetime Achievement Award
  • Research Achievement Award
  • Educational Achievement Award
  • Service Achievement Award
  • Mentoring Achievement Award
  • Model of Excellence Award
  • Community Pediatric Educator Award
DEPARTMENT OF PEDIATRICS TO GATHER SUPPLIES FOR HURRICANE VICTIMS

The department is gathering supplies to help with the devastation left behind in Haiti from Hurricane Matthew. This supply drive will begin on Wednesday, Oct. 19 and end on Tuesday, Nov. 1. Labeled donation boxes will be placed in each division where faculty, staff, fellows and residents can drop off goods. Attached is the flyer. Please contact Samantha Hill, M.D., Adolescent Medicine Fellow, with any questions or to get involved. 
DR. CRON RECEIVES CENTER FOR GENOMIC MEDICINE PILOT GRANT

The UAB-HudsonAlpha Center for Genomic Medicine has awarded the second round of pilot grants. The three pilot grants have been given to collaborative teams comprised of one researcher from UAB and one from HudsonAlpha to pursue novel investigations. The pilot grant funding is $100,000 per year for up to two years. Randy Cron, M.D., Ph.D., Pediatric Rheumatology, received one of the three grants with Devin Absher, Ph.D., HudsonAlpha. Click here for more information. 
DR. ABDUL-LATIF RECEIVES ARGUS AWARD

Students from the UAB School of Medicine named 20 faculty and six clinical departments winners of the 2016 Argus Awards. Hussein Abdul-Latif, M.D., Pediatric Endocrinology, received the Argus Award for Birmingham Clinical Educator.

Created in 1996, the Argus Awards give medical students the chance to honor their mentors, professors, courses and course directors for outstanding service to medical education. Faculty members are nominated by course evaluations, and students vote to select award winners in each category.

Argus Award recipients and nominees were honored at a reception on Friday, Oct. 7 at Children’s Harbor. Click here to view Department of Pediatrics Nominees or here to view the all winners. Click here for photos from the event. 
KC FIT 5K NEEDS YOU! 

Please see the below information about the upcoming 5K race for a great opportunity to support one of our own, Michele Kong, M.D., Pediatric Critical Care, and KultureCity!  We are inviting all employees of Children's of Alabama and UAB Pediatrics to participate! Click here for more information and to register

When: December 17,
2016 at 8 a.m.
Who: Children’s of Alabama employees, their families, coworkers, and friends
What: KC Fit 5K in Vestavia Hills 
Why: Autistic children are not limited by their diagnosis and deserve a future without limits. https://www.kulturecity.org/
Cost: $35
Team: Sign up under “Kulture Elves”    
Contact: Robin Greer if you have any questions
Attire: Dress like an elf for the day of the race to help our team win best spirit award!
SAVE THESE DATES
2016 FACULTY CORPORATE COMPLIANCE 

Mark your calendars for Grand Rounds on October 27, 2016. Brian T. Bates, CPA, CHC, MAc, Chief Compliance Officer, UAB Medicine/UAB Health System, and Stephen W. Stair, MD, FAAP , Clinical Associate Professor, UAB Division of Internal Medicine and Medical Compliance Officer, University of Alabama Health Services Foundation, will present  “Compliance 2016: The Good, The Bad and The Ugly” at noon in the Bradley Lecture Center. 
PEDIATRIC GASTROENTEROLOGY FACULTY CANDIDATE 

Gillian O. Noel, M.D., MSCS
Pediatric Advanced Hepatology/Transplant Fellowship
Children’s Healthcare of Atlanta
Atlanta, GA

Dr. Noel will present, "Outcomes in Pediatric Liver Transplantation: Does Race Play a Role in Graft Survival?" at Walter Cain Surgical Auditorium (Lowder 3rd Floor) on Oct. 24, at 4:30 p.m. Download the flyer
PEDIATRIC PULMONARY & SLEEP MEDICINE VISITING FACULTY 

Ignacio Tapia, MD
Assistant Professor
Children’s Hospital of Philadelphia
Philadelphia, Pennsylvania

Dr. Tapia will present “Respiratory Afferent Sensory Processing in Children with OSAS” in the Benton Conference Room (Lowder 6th Floor) on Oct. 21 at 10:30 - 11:30 a.m. Download the flyer

 
CHILD HEALTH INVESTIGATIVE FORUM (CHIF) - OCTOBER 2016
Bradley Conference Center
Noon (lunch provided)

OCTOBER 21
TGF-Beta Pathobiology in CF Lung Disease
Tom Harris, M.D.
Assistant Professor
Pediatric Pulmonary
PEDIATRIC RESIDENCY UPDATE
SENIOR TALKS - SUPPORT PGY 3 & 4 RESIDENTS!

Join us for Senior Talks Monday, Oct. 17 at noon in the Bradley Lecture Center

Ashley Elam (MedPeds PGY 4) - Management of Tetralogy of Fallot Patients Post-Repair
Kristine Sawyer (Pediatrics PGY 3) - Vaccine Hesitancy

 
FROM THE PEDIATRIC OFFICE OF FACULTY DEVELOPMENT (OFD) 
4TH FRIDAYS LUNCH & LEARN

OCTOBER 28 

Managing Conflict

Duanna Pang-Dokland
Leadership Coach
Bradley Lecture Center
Noon - 1 p.m.
Click here for the flyer and educational objectives.

EACC OCTOBER EVENTS 

Below are the events the Employee Assistance and Counseling Center (EACC) will be hosting for the month of October.
Pilates - Mondays and Wednesdays, October 17, 2016 – December 19,
2016 5:15 p.m. – 6:15 p.m. No registration necessary.
Gentle Yoga - Tuesdays and Thursdays October 18, 2016 – December 22,
2016 5:15 p.m. – 6:15 p.m. No registration necessary.
2016 Domestic Violence Conference - Tuesday, October 25, 2016; 8:00 a.m.- 5:00 p.m. Space is still available. Register online now.
For the month of 
October the EACC is sponsoring a Toiletry Drive to benefit Domestic Violence Victims. Donation boxes are in various locations around campus. Please see flyer for more details.
FROM THE PEDIATRIC RESEARCH OFFICE (PRO)
FUNDING
 
CCTS 2017 Partner Network Multidisciplinary Pilot Program
The CCTS annual pilot program funds new interdisciplinary clinical and translational projects that are consistent with the CCTS mission and show promise for growing into mature research programs. The first step is to request a Letter of Intent (LOI) form from Dr. Jennifer Croker (jcroker@uab.edu), Executive Administrator, CCTS Research Commons. LOIs are due Oct. 17 at 5 p.m. 
 
UAB Funding Opportunity – Researchers Omnibus Survey of Alabama
The Center for the Study of Community Health will fund up to four proposals for a total of $30,000. Awards provide UAB faculty investigators access to the UAB School of Public Health's Survey Research Unit to develop, collect, and compile preliminary survey data. Four-page proposals are due Oct. 31 before 5 p.m.
 
 SEMINARS AND TRAINING
 
CCTS PSDS: How to Review a Paper in Under an Hour
Dr. Victor Darley-
Usmar, PhD, vice chair for research, UAB Department of Pathology, will present this seminar on Oct. 20 from 8:30-10 a.m. in PCAMS (located at 1924 7th Ave So). Topics include the peer review process, role of reviewers, journal goals, review format, and steps for expedient and fair reviewing. To register, click here.
 
Clinical and Translational Science (CTS) Training Program
This six-month certificate program provides training in clinical and translational research, including approximately 50 hours of didactic instruction as well as interactive experiences.  Classes, which run from January to June, take place on Wednesdays from 8 - 10 a.m. at
PCAMS (located at 1924 7th Ave So). Applications are due Oct. 24 by 5 p.m. For more information, please contact Jean Lambert (jeanl@uab.edu).
 
POSTPONED: The PRO Series – Tuesday, Oct. 18 at 1 p.m.
October’s speaker has been called out of town, so there will be no seminar on Oct. 18. 
 
SAS Training
There has been a request for SAS Training. If you are interested, please email Cheryl Perry (cperry@uab.edu) so we can determine whether there is enough interest for a group training.  
PUBLICATIONS
BMC Cardiovasc Disord. 2016 Oct 4;16(1):187. Rationale and design of the Children's Oncology Group (COG) study ALTE1621: a randomized, placebo-controlled trial to determine if low-dose carvedilol can prevent anthracycline-related left ventricular remodeling in childhood cancer survivors at high risk for developing heart failure. Armenian SH, Hudson MM, Chen MH, Colan SD, Lindenfeld L, Mills G, Siyahian A, Gelehrter S, Dang H, Hein W, Green DM, Robison LL,Wong FL, Douglas PS, Bhatia S.
The manuscript describes the rationale for a  Children’s Oncology Group-wide double-blinded, placebo controlled trial that will provide much-needed information regarding a physiologically plausible pharmacological risk-reduction strategy for childhood cancer survivors at high risk for developing anthracycline-related heart failure.


Curr Opin Pediatr. 2016 Feb;28(1):81-5. doi: 10.1097/MOP.0000000000000305. Advances in the prevention and treatment of congenital cytomegalovirus infection. James SH, Kimberlin DW.

J Cyst Fibros. 2016 Oct 1. pii: S1569-1993(16)30607-5. doi: 10.1016/j.jcf.2016.09.005. Therapeutic benefit observed with the CFTR potentiator, ivacaftor, in a CF patient homozygous for the W1282X CFTR nonsense mutation. Mutyam V, Libby EF, Peng N, Hadjiliadis D, Bonk M, Solomon GM, Rowe SM.
In an example of precision medicine, we evaluated the cells of a CF patient with a rare CFTR mutation with the novel CFTR potentiator ivacaftor. After demonstrating efficacy, we then treated the patient in a n of 1 trial and showed stabilization of lung function, reduced exacerbations, and improved weight gain, indicating this mutation may be a target for CFTR potentiator therapy.

MBio. 2016 Oct 4;7(5). pii: e01554-16. doi: 10.1128/mBio.01554-16. Phosphorylation of Golgi Peripheral Membrane Protein Grasp65 Is an Integral Step in the Formation of the Human Cytomegalovirus Cytoplasmic Assembly Compartment. Rebmann GM, Grabski R, Sanchez V, Britt WJ.
One of the distinct morphological features observed in cells infected with human cytomegalovirus (HCMV) is the formation of a membranous assembly compartment (AC) where the virus acquires its mature envelope, which is necessary for infectivity. The outer boundary of the AC consists of the Golgi apparatus, which is extensively remodeled forming a ring-like structure, in contrast to its ribbon-like appearance observed in uninfected cells. Although the AC was characterized over 20 years ago, the mechanisms driving changes in Golgi morphology during HCMV infection have not been identified. In this study, we have determined that HCMV infection leads to modification of Grasp65, a cellular Golgi protein, to disrupt Golgi structure and that reorganization of the Golgi is required for formation of the AC and production of infectious virus. 


Pediatr Crit Care Med. 2016 Oct;17(10):1001-1003. Another Piece to the Puzzle: "A Riddle Wrapped in a Mystery Inside an Enigma"-Winston Churchill. Tofil NM, Richter RP, Prabhakaran P.

JAMA Pediatr. 2016 Oct 10. doi: 10.1001/jamapediatrics.2016.2016. Cost-effectiveness of Universal and Targeted Newborn Screening for Congenital Cytomegalovirus Infection. Gantt S, Dionne F, Kozak FK, Goshen O, Goldfarb DM, Park AH, Boppana SB, Fowler K.

In a cost-effectiveness study that compared universal (for all newborns) or targeted cCMV screening (newborns with a failed universal newborn hearing screen) with no screening under a wide range of assumptions regarding the US costs of testing, treatment, and hearing loss related to cCMV infection, universal and targeted cCMV screening were relatively low cost, or cost saving if costs related to lost productivity were included. The data on costs of newborn CMV screening and CMV-related hearing loss were derived from the UAB CHIMES study and natural history studies of congenital CMV at UAB over several decades. 

JAMA Pediatr. 2016 Oct 10. doi: 10.1001/jamapediatrics.2016.1936 Association of Neurodevelopmental Outcomes and Neonatal Morbidities of Extremely Premature Infants With Differential Exposure to Antenatal Steroids. Chawla S, Natarajan G, Shankaran S, Pappas A, Stoll BJ, Carlo WA, Saha S, Das A, Laptook AR, Higgins RD; National Institute of Child Health and Human Development Neonatal Research Network.
A complete course of antenatal steroids given over a 24 hour period to women at risk of imminent preterm delivery between 23-34 weeks reduces death and neurodevelopmental impairment in survivors. However, it is unclear if partial treatment (even a single dose) is beneficial. This study confirms the findings by investigators from UAB (Travers et al) that partial treatment with antenatal steroids affords most of the benefits of antenatal steroids including
reduction in mortality and reduction in neurodevelopmental impairment in survivors. 
 
The deadline for submission of information for inclusion in the FYI Fridays newsletter is 10 a.m. on the preceding Thursday.
 
Click here to submit information to FYI Fridays.
FYI FRIDAYS ARCHIVE
Copyright © 2016 The UAB Department of Pediatrics, All rights reserved.






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