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NOVEMBER 20, 2015
NOVEMBER NEW FACULTY SPOTLIGHT 

The Department of Pediatrics welcomed two new faculty members during the month of November. Madhuri Penugonda, M.D., joined the Pulmonary faculty. Dr. Penugonda is situated in Huntsville, and will be doing clinic several times a month at Children's of Alabama. Alexandra Martin, M.D., joined the Endocrinology faculty after completing her fellowship here. She will be seeing patients and is the principal investigator of a clinical trial for children with diabetes (see below).   
NEW SPECIALTY CLINIC - DEVELOPMENTAL MEDICINE 

The Department of Pediatrics would like to formally announce its recently launched Developmental Medicine Clinic (DMC).  The clinic, which is located in Clinic A at Children’s of Alabama’s Park Place Building, serves children of all ages for whom parents, health care providers, or other caregivers have identified concerns related to development, behavior, social skills, and/or learning. Drs. Justin Schwartz and Snehal Khatri, developmental-behavioral pediatricians, staff the clinic and provide expertise in conditions such as:
  • Attention Deficit/Hyperactivity Disorder
  • Autism Spectrum Disorder
  • Intellectual Disabilities
  • Learning Disabilities
  • Developmental Delays
  • Developmental or behavioral assessment of children with genetic conditions (e.g. Down syndrome, Williams syndrome, Prader-Willi, etc.) or other medical conditions
  • Management of common behavioral conditions (sleep, toileting, etc.)
The clinic is currently accepting new patient referrals. For more information about the clinic, what to expect from a visit, downloadable intake packets and referral forms, and more, please visit the website.
 
TWO FACULTY MEMBERS ELECTED TO SOCIETY OF PEDIATRIC RESEARCH (SPR) 


Congratulations to Trent Tipple, M.D., Neonatology, and Gregory Friedman, M.D., Pediatric Hematology/Oncology,  on their recent election to the Society of Pediatric Research (SPR).
DRS. MARTIN AND MCCORMICK RECEIVE $612,000 GRANT FROM JDRF

The Juvenile Diabetes Research Foundation (JDRF) recently awarded Alexandra Martin, M.D., and Ken MCormick, M.D., Pediatric Endocrinology, a grant for their clinical research trial titled, "The Effect of GABA or Combination GABA/GAD on the Progression of Type 1 Diabetes Mellitus in Children." The project is funded for $612,000. 
AAP'S CATCH GRANT AWARDED

Congratulations to community pediatrician Stephanie Denton, M.D., FAAP. She was awarded the American Academy of Pediatrics (AAP)  Community Access to Child Heath (CATCH) grant for her learning disability program Alabama Game Changers. Their non-profit organization performs dyslexia evaluations and provides evidence based interventions. For more CATCH grant information, click here
PEDIATRICIANS FIRST TO ATTAIN PERFORMANCE IMPROVEMENT CONTINUING MEDICAL EDUCATION

The Alabama Child Health Improvement Alliance (ACHIA), in partnership with the University of Alabama at Birmingham's (UAB) Division of eLearning and Professionals Studies (eLPS) and UAB Division of CME, has become the first organization in Alabama to offer Performance Improvement Continuing Medical Education (PI CME) for exclusively practice-based physicians through its current developmental screening project, Help Me Grow/Project LAUNCH.

Click here to continue reading the press release on AL.com or UAB News
 
CHILDREN'S OF ALABAMA SELECTED AS CHA PEDIATRIC QUALITY AWARD SEMIFINALIST

The Pediatric Intensive Care Unit (PICU) project, “Decreasing Hospital Length of Stay for Post-operative Adolescent Spinal Fusion Patients,” was selected as one of three finalists in the Children’s Hospital Association (CHA) Pediatric Quality Award (PQA) in the category of Waste Reduction/Improved Efficiency. This project represents an inter-professional effort led by Leslie Hayes, M.D., in concert with PICU nursing, PICU nurse practitioners and Joe Khoury, M.D., from the Children's of Alabama orthopedic group. All semifinalists present their projects at the National CHA Quality and Safety Conference in New Orleans, LA in March 2016, where the overall winner will be selected.
 
EMERGENCY MEDICINE FUNDED BY FEMA FOR SOUND OFF PROJECT

The UAB Pediatrics division of Emergency Medicine received funding from Federal Emergency Management Agency (FEMA) for a community project called Sound Off. The project led by Kathy Monroe, M.D., and Michele Nichols, M.D., is a starter site for the Sound Off FEMA Grant, which works with Birmingham Fire and Rescue and a local school to provide fire safety education. 
IN THE NEWS...

Click here to read the article in Alabama Newscenter, Sickle Cell Disease Cure in Sights of UAB Stem Cell Institute, which features sickle cell researchers, Tim M. Townes, director of UAB Stem Cell Institute and Fred Goldman, M.D., director of the Lowder Pediatric Blood and Marrow Transplantation Program at Children’s of Alabama. 
CALLING ALL PEDIATRICIANS!

The Emergency Department is offering moonlighting shifts in the Emergency Department area to see non-urgent patients now through the winter. These shifts will be from 6 p.m. to midnight during the week, noon to 8 p.m. and 4 p.m. to midnight on the weekends. You would be seeing non-urgent patients only and expected to see three to four patients per hour (emergency department attendings or fellows will always be present for consultations). All documentation is done in Allscripts/i-Connect. If interested, please email Kathy Monroe, M.D. for more information. 
REMINDER: DID YOU MISS YOUR DIVISION'S LISTENING SESSION?
 
The Office of Faculty Development
Invites you to participate in a
TOWN HALL MEETING
To discuss thoughts and ideas around
Mentoring
Work/Life Integration
Thursday, December 3
3:30 - 4:30 p.m.

Bradley Lecture Center
NOMINATIONS OPEN FOR EXCELLENCE IN TEACHING AWARDS

Nominations are being accepted for the President's Award for Excellence in Teaching. The award recognizes full-time regular UAB faculty who have demonstrated exceptional accomplishments in teaching. The selection criteria and nomination form are online.
FROM THE PEDIATRIC RESEARCH OFFICE (PRO)

NIH Fundamentals and Resources
Geeta Chhabra, Grants and Contracts Specialist in the Department of Pediatrics, will present “NIH Fundamentals and Resources” on Monday, Nov. 30 from noon to 1 p.m. in the Bradley Center.  Lunch is available to the first 20 attendees.  The presentation will provide an overview of the Resources, Understanding the NIH Grants Process, and answers to common grant-submission questions. Target audience:  Faculty and Administrators
 
ALPHABET SOUP? PMCIDs, MyNCBI AND THE SciENcv BIOSKETCH GENERATOR
Don't miss the second part of this workshop, presented by Lee Vucovich, Associate Professor and Chair, Lister Hill Library Reference Department, exploring how to use the SciENcv tool to generate the new 5-page NIH Biosketch.  It will be held on Dec. 2 from 3 - 4 p.m. in the Bradley Lecture Center.
UAB EACC UPCOMING PROGRAMS AND EVENTS

Recognizing Arts and Health Month - Tuesday, Nov.  24, 2015; 10 a.m. - 12:30 p.m. Stop by to see Employee Assistance and Counceling Center (EACC ) Art therapist Carrie Ezell and learn more about how art therapy can help you. 
All are welcome to come play or just give your support! 
CDE BUZZ WORDS

It’s that time again…Rhinovirus, Adenovirus, and Flu A and B are spreading, and the kiddos we treat are coming in with these viruses. In babies, we are seeing a lot of bronchiolitis, and in the older patients these viruses are making their presence known with more status asthmaticus and pneumonia. Though these children will have an individualized plan of care, one common diagnosis most of these patients will share is Acute Respiratory Failure. The CDE Nurses have found that there are many misconceptions regarding this diagnosis, and we hope to clear up the biggest one this week! Click here for more.       
RESEARCH
PEDIATRIC RESIDENCY UPDATE

Congratulations, Dr. Carlie Stein!
Third year Med-Peds resident Carlie Stein, M.D., was selected to be part of the Chief Quality Resident Program. She is one of only five residents chosen university-wide for this program.
GRANT NEWS
 
David Askenazi, M.D., (Ped - Nephrology) Reduction of Nephrotoxic Medication-Associated Acute Kidney Injury in Children - NINJA CINCINNATI CHILDREN'S HOSPITAL. $22,050. 04/01/2015 - 03/31/2016. 

Smita Bhatia, M.D., (Ped - Hematology/Oncology) Bone Marrow Transplant Survivor Study - 2 Leukemia and Lymphoma Society. $600,000. 10/01/2015 - 09/30/2017.

Mitchell Cohen, M.D., (Pediatrics Chair Office) IRONWOOD PHARMACEUTICALS, INC. $151,062. 10/20/2015 - 10/19/2016. 

Tina Simpson, M.D., MPH, (Ped - Adolescent Medicine) Leadership Education in Adolescent Health (LEAH) Health Resources and Services Administration/DHHS. $374,496. 07/01/2015 - 06/30/2016.

Smita Bhatia, M.D., (Ped - Hematology/Oncology) Comprehensive Approach to Improve Medication Adherence in Pediatric ALL St. Baldrick's Foundation. $46,068. 07/01/2015 - 06/30/2016.

Jeffrey Alten, M.D., (Ped - Critical Care) Impact of Hypothermia on Midazolam/Morphine Pharmacokinetics CHILDREN'S HOSPITAL (PHILADELPHIA). $10,500. 04/01/2015 - 03/31/2016.

Matthew Kutny, M.D., (Ped - Hematology/Oncology) AALL1331: Risk-Stratified Randomized Phase III Testing of Blinatumomab (IND#100135, NSC#765986) in First Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL) CHILDREN'S HOSPITAL (PHILADELPHIA). $9,800. 10/23/2015 - 10/22/2016. 

Julie Wolfson, M.D., (Ped - Hematology/Oncology) Adolescents and Young Adults with Cancer: Race, Ethnicity & Treatment Site St. Baldrick's Foundation. $118,570. 12/01/2015 - 11/30/2016.

RECENT REVIEWS AND PUBLICATIONS
 
Clin Pediatr (Phila). 2015 Mar;54(3):257-63. doi: 10.1177/0009922814551133. Comparison of pediatric and general emergency medicine practice patterns in infants with fever. Vanguru L, Redfern RE, Wanjiku S, Sunallah R, Mukundan D, Vemuru L.
 
 2015 Nov 1;28(11-12):1373-8. doi: 10.1515/jpem-2014-0394. Hypomagnesemia due to two novel TRPM6 mutations. Coulter M, Colvin C, Korf B, Messiaen L, Tuanama B, Crowley M, Crossman DK, McCormick K.

Pediatr Emerg Care. 2015 Nov 6. Human Immunodeficiency Virus Risk Factors and Beliefs Reported by Families Presenting to a Pediatric Emergency Department. Barbour WL, Rodgers JB, Wang HE, Donnelly JP, Tapley AM, Galbraith JW.

Pediatr Nephrol. 2015 Nov 16. Smaller circuits for smaller patients: improving renal support therapy with Aquadex™.
Askenazi D, Ingram D, White S, Cramer M, Borasino S, Coghill C, Dill L, Tenney F, Feig D, Fathallah-Shaykh S.
Providing renal support for small children is very challenging and is associated with significant morbidity and mortality.  We present a case series of small children (n = 12) who received continuous venovenous hemofiltration (CVVH) via an Aquadex™ machine (ECV = 33 ml) with 30 ml/kg/h of prereplacement fluids at Children's of Alabama between December 2013 and April 2015. We used 101 circuits over 261 days to provide CVVH for 12 children (median age 30 days; median weight 3.4 kg). Median CVVH duration was 14.5 days [interquartile range (IQR) = 10; 22.8 days]. Most circuits were routinely changed after 72 h. Five of 101 (5 %) initiations were associated with mild transient change in vital signs. Complications were infrequent.  Most patients (7/12, 58 %) were discharged from the intensive care unit; six of them (50 %) were discharged home.
CVVH machines with low ECV can enable clinicians to provide adequate, timely, safe, and efficient renal support to small, critically ill infants.


Pediatr Nephrol. 2015 Nov 16. Acute changes in fluid status affect the incidence, associative clinical outcomes, and urine biomarker performance in premature infants with acute kidney injury. Askenazi D, Saeidi B, Koralkar RAmbalavanan N, Griffin RL.
During the first postnatal weeks, infants have abrupt changes in fluid weight that alter serum creatinine (SCr) concentration, and possibly, the evaluation for acute kidney injury (AKI). We performed a prospective study on 122 premature infants to determine how fluid adjustment (FA) to SCr alters the incidence of AKI, demographics, outcomes, and performance of candidate urine biomarkers. We found that the incidence of AKI was lower using the FA-SCr vs. SCr definition [(23/122 (18.8 %) vs. (34/122 (27.9 %); p < 0.05)], with concordance in 105/122 (86 %) and discordance in 17/122 (14 %). Candidate urine AKI biomarkers performed better under the FA-SCr than SCr definition, especially on day 4 and days 12-14. Adjusting SCr for acute change in fluid weight may help differentiate SCr rise from true change in renal function from acute concentration due to abrupt weight change.


 
POSTER AND PRESENTATION ANNOUNCEMENTS 
 
Ashraf A. Nov. 15, 2015. Birmingham, AL. Physical Activity and Diabetes. The Alabama State Association for Health, Physical Education, Recreation and Dance (ASAHPERD) Annual Meeting.

Massey K, Kant S, King W, Roney L, Violano P, Monroe K. Nov. 13-15, 2015. Fort Lauderdale, FL. Evaluating Distracted Driving Behaviors in Parents of Children in Suburban and Rural Areas of Alabama (abstract). Annual Injury Free Colaition for Kids Conference. 

Nichols E, Hardiwick W, Lawson V, King W, Nichols M, Monroe K. Nov. 13-15, 2015. Fort Lauderdale, FL. Risky Teen Driving Behaviors and Factors Influencing Teens (abstract). Annual Injury Free Colaition for Kids Conference. 
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