Newsletter of the Meyer Cancer Center               February 2017
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FUTURE SO BRIGHT: We've spent the beginning of the year reflecting on the past, making plans for the present, and looking ahead to the future. The result? Our first proper annual report. Read it here >>

Old drug, new hope 

Phenformin, once used to treat diabetes may be of big benefit to melanoma and other skin cancer patients
Read more>>

Cancer corps

A WCM team is joining the International Cancer Expert Corps to create a hub of global outreach for cancer care.
Read more>>


A method to map CAR-T cells throughout the body could improve the safety & efficacy of immunotherapy.
Read more>>


ABEL INVESTIGATOR: Dr. Samie Jaffrey, the Greenberg-Starr Professor of pharmacology, has received the 2017 John J. Abel Award in Pharmacology from the American Society for Pharmacology and Experimental Therapeutics.

OUTSTANDING INVESTIGATOR: Meyer director Lewis Cantley will receive $4.2 million over 7 years to continue his research into PI3K and cancer metabolism.

YOUNG INVESTIGATOR: Loredana Puca, Ph.D., a researcher working with Himisha Beltran, M.D., and Mark Rubin, M.D. received a Lori Milken–PCF Young Investigator Award from the Prostate Cancer Foundation.

In the headlines

Medical Marvels: Life-saving treatment for chronic leukemia
abc7NY ~ February 8, 2017
Richard Furman, M.D. and patient Robert Frank Azopardi were featured on the abc7NY Medical Marvels series. 

When should you be screened? Important cancer tests you shouldn't miss
TODAY Show ~ January 5, 2017
Felice Schnoll-Sussman, M.D., appeared on the TODAY Show to review cancer screening guidelines by age.

Copper toned research trial offers new hope in finding a cure for cancer
NY1 ~ January 4, 2017
TV coverage of Linda Vahdat's copper depletion trial, and the crowdfunding initiative she has started to fund it.

See more>>

Funding opportunities

Rising Tide Foundation – Various
ASPIRE Oncology/Hematology Research Awards Program – Advanced breast cancer, acute leukemia
Lewin Fund – Women's cancers; $50,000

See more>>


Recent Publications


The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein.
Chen M, Nowak DG, Narula N, Robinson B, Watrud K, Ambrico A, Herzka TM, Zeeman ME, Minderer M, Zheng W, Ebbesen SH, Plafker KS, Stahlhut C, Wang VM, Wills L, Nasar A, Castillo-Martin M, Cordon-Cardo C, Wilkinson JE, Powers S, Sordella R, Altorki NK, Mittal V, Stiles BM, Plafker SM, Trotman LC.
J Cell Biol. 2017 Feb 13. pii: jcb.201604025. doi: 10.1083/jcb.201604025.

Effective combination therapies for B cell lymphoma predicted by a virtual disease model.
Du W, Goldstein R, Jiang Y, Aly O, Cerchietti L, Melnick AM, Elemento O.
Cancer Res. 2017 Jan 27. pii: canres.0476.2016. doi: 10.1158/0008-5472.CAN-16-0476.

Matrix stiffening promotes a tumor vasculature phenotype.
Bordeleau F, Mason BN, Lollis EM, Mazzola M, Zanotelli MR, Somasegar S, Califano JP, Montague C, LaValley DJ, Huynh J, Mencia-Trinchant N, Negrón Abril YL, Hassane DC, Bonassar LJ, Butcher JT, Weiss RS, Reinhart-King CA.
Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):492-497. doi: 10.1073/pnas.1613855114

Increase in Prostate Cancer Distant Metastases at Diagnosis in the United States.
Hu JC, Nguyen P, Mao J, Halpern J, Shoag J, Wright JD, Sedrakyan A.
JAMA Oncol. 2016 Dec 29. doi: 10.1001/jamaoncol.2016.5465.

Save the Date

March 15, 2017 

Meyer Cancer Center Seminar Series

Rakesh K. Jain, Ph.D.
Harvard Medical School

March 15-16, 2017

The Need to Accelerate Therapeutic Development — Must Randomized Controlled Trials Give Way?

Janet Woodcock, M.D.
Robert Califf, M.D.


New York Academy of Sciences

April 7, 2017

Meyer Cancer Center Retreat

May 16-20, 2017 

Mechanisms of Metabolic Signaling
Cold Spring Harbor


See more>>

#WeAreWCM: Chris Barbieri is the latest MCC member to become the face of WCM.
View his video here, then check out our other superstars:
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